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Effects of temporal IFNγ exposure on macrophage phenotype and secretory profile: exploring GMP-Compliant production of a novel subtype of regulatory macrophages (Mreg IFNγ0 ) for potential cell therapeutic applications.

Karina ZittaLars HummitzschFrank LichteFred FändrichMarkus SteinfathChristine EimerSebastian KapahnkeMatthias BuergerKatharina HessMelanie RuschRene RuschRouven BerndMartin Albrecht
Published in: Journal of translational medicine (2024)
may therefore have the potential to serve as cellular therapeutics for clinical applications beyond those covered by M2-like Mreg, including immunomodulation and tumor treatment.
Keyphrases
  • immune response
  • dendritic cells
  • single cell
  • adipose tissue
  • human health
  • small molecule
  • transcription factor
  • mesenchymal stem cells
  • cystic fibrosis
  • bone marrow
  • replacement therapy
  • smoking cessation