Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.
Guilherme PovalaBruna BellaverMarco Antônio De BastianiWagner S BrumPamela C L FerreiraAndrei BiegerTharick A PascoalAndrea L BenedetDiogo O SouzaRicardo M AraujoBruno ZattPedro Rosa-NetoEduardo R Zimmernull nullPublished in: Cell & bioscience (2021)
Our results demonstrate that, by applying a refined ML analysis, a combination of Aβ isoforms can predict T+ and N+ with a high AUC. CSF proteomics analysis highlighted a promising group of proteins that can be further explored for improving T+ and N+ prediction.
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