Complement components C3b and C4b as potential reliable site-specific diagnostic biomarkers for periodontitis.
Ren-Yeong HuangFang-Yi TsengChia-Dan ChengThomas E Van DykeCheng-En SungJhong-Jhe YouPei-Wei WengYi-Shing ShiehWan-Chien ChengPublished in: Journal of periodontal research (2023)
Locally deposited C3b and C4b were positively correlated with periodontitis severity and recognized as site-specific diagnostic biomarkers for clinicopathological features in periodontitis. The association between the C3b and C4b network and periodontitis may be further understood and provide a basis for the development of novel screening as well as diagnostic and therapeutic strategies for periodontitis.
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