Computed tomography-based body composition measures in COPD and their association with clinical outcomes: A systematic review.
John M NicholsonCamila E OrssoSahar NourouzpourBrenawen ElangeswaranKaran ChohanAni Orchanian-CheffLee FidlerSunita MathurDmitry RozenbergPublished in: Chronic respiratory disease (2022)
There was significant variability in CT-body composition measures. In several studies, low muscle mass was associated with increased disease severity and lower HRQL, whereas adiposity with cardiovascular disease/risk factors. Given the heterogeneity in body composition measures and clinical outcomes, the prognostic utility of CT-body composition in COPD requires further study.
Keyphrases
- body composition
- computed tomography
- resistance training
- bone mineral density
- cardiovascular disease
- dual energy
- image quality
- chronic obstructive pulmonary disease
- risk factors
- contrast enhanced
- positron emission tomography
- lung function
- magnetic resonance imaging
- insulin resistance
- single cell
- magnetic resonance
- metabolic syndrome
- physical activity
- postmenopausal women
- weight gain
- air pollution