Development of a core outcome set to determine the overall treatment success of acute uncomplicated appendicitis in children: a study protocol.

Frances C Sherratt Simon EatonErin WalkerLucy BeasantJane M BlazebyBridget YoungEsther CrawleyWendy W WoodNigel J Hall

Published in: BMJ paediatrics open (2017)

COS development is part of CONservative TReatment of Appendicitis in Children - a randomised controlled Trial (Feasibility) (CONTRACT) study, for which full ethical approval for CONTRACT has been granted. The COS development study is registered with the COMET Initiative in May 2017 (http://www.comet-initiative.org/studies/details/987).

Keyphrases

study protocol
quality improvement
clinical trial
liver failure
decision making
replacement therapy
acute respiratory distress syndrome
extracorporeal membrane oxygenation
smoking cessation