Decoding Patient Heterogeneity Influencing Radiation-Induced Brain Necrosis.
Ibrahim M ChamseddineKeyur D ShahHoyeon LeeFelix EhretSchuemann JanAlejandro BertoletHelen A ShihHarald PaganettiPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Key patient variables critical to understanding brain necrosis post-RT were identified, aiding the study of dosimetric impacts and providing treatment confounders and moderators. This pipeline aims to enhance outcome assessments by revealing at-risk patients, offering a versatile tool for broader applications in RT to improve treatment personalization in different disease sites.