Epigenome alterations in food allergy: A systematic review of candidate gene and epigenome-wide association studies.

Ramia Safar Abderrahim OussalahLina MayorgaStefan ViethsDomingo BarberMaria Jose TorresJean-Louis Guéant

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2023)

This review highlights the involvement of epigenomic alterations of loci in Th1/Th2 and regulatory T cell differentiation in both candidate gene studies and EWAS. These alterations provide a better insight into the mechanistic aspects in FA pathogenesis and may guide the development of epigenome-based biomarkers for FA.

Keyphrases

dna methylation
genome wide
copy number
case control
gene expression
genome wide identification
genome wide association study