Direct Oral Anticoagulants in the Prevention of Venous Thromboembolism Following Surgery for Hip Fracture in Older Adults: A Population-Based Cohort Study.
En Lin GohPratha Kumari GurungShaocheng MaTimothy PilpelJames Henderson DaleAngela KannanSambandam AnandPublished in: Geriatric orthopaedic surgery & rehabilitation (2020)
In the present study of a carefully selected cohort of patients, the effect of DOACs in reducing the risk of VTE following surgery for hip fracture in the older adults was comparable to LMWH. However, a trend toward increased risk of hemorrhage was noted. Larger prospective studies will be required to identify patients who will benefit the most from treatment.
Keyphrases
- venous thromboembolism
- hip fracture
- direct oral anticoagulants
- minimally invasive
- coronary artery bypass
- end stage renal disease
- atrial fibrillation
- physical activity
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- chronic kidney disease
- prognostic factors
- surgical site infection
- acute coronary syndrome
- patient reported outcomes