Epilepsy after acute central nervous system complications of pediatric hematopoietic cell transplantation: A retrospective, multicenter study.
Luca BergonziniDavide LeardiniRoberta RaoThomas FoiadelliMaura FaraciMaria Margherita MancardiGiulia NobileAlessandro OrsiniSalvatore SavastaFrancesca GottardiAnna FettaTommaso MinaGabriella CasazzaMaria Cristina MenconiDario PrunaRosa Maria MuraAntonio PiroddiPaola RucciRiccardo MasettiDuccio Maria CordelliPublished in: Seizure (2024)
A higher occurrence of epilepsy has been observed in our cohort compared to the general population. Acute symptomatic SE during HCT was associated with a higher risk of long-term epilepsy. Pediatric patients with CNS complications during HCT could benefit from specific neurological follow-up. Further studies are needed to characterize mechanisms of epileptogenesis in pediatric patients undergoing HCT.