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Epilepsy after acute central nervous system complications of pediatric hematopoietic cell transplantation: A retrospective, multicenter study.

Luca BergonziniDavide LeardiniRoberta RaoThomas FoiadelliMaura FaraciMaria Margherita MancardiGiulia NobileAlessandro OrsiniSalvatore SavastaFrancesca GottardiAnna FettaTommaso MinaGabriella CasazzaMaria Cristina MenconiDario PrunaRosa Maria MuraAntonio PiroddiPaola RucciRiccardo MasettiDuccio Maria Cordelli
Published in: Seizure (2024)
A higher occurrence of epilepsy has been observed in our cohort compared to the general population. Acute symptomatic SE during HCT was associated with a higher risk of long-term epilepsy. Pediatric patients with CNS complications during HCT could benefit from specific neurological follow-up. Further studies are needed to characterize mechanisms of epileptogenesis in pediatric patients undergoing HCT.
Keyphrases
  • patients undergoing
  • cell cycle arrest
  • risk factors
  • risk assessment
  • temporal lobe epilepsy
  • liver failure
  • drug induced
  • respiratory failure
  • intensive care unit
  • case control
  • extracorporeal membrane oxygenation