Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction after Lung Transplant.
Edward CantuJoshua M DiamondYoshikazu SuzukiJared LaskyChristian SchauflerBrian LimRupal ShahMary PorteousDavid J LedererSteven M KawutScott M PalmerLaurie D SnyderMatthew G HartwigVibha N LamaSangeeta BhoradeChristian BermudezMaria CrespoJohn McDyerKeith WilleJonathan OrensPali D ShahAnn WeinackerDavid WeillDavid WilkesDavid RoeChadi HageLorraine B WareScarlett L BellamyJason D Christienull nullPublished in: American journal of respiratory and critical care medicine (2019)
The PGD consensus definition can be simplified by combining lower PGD grades. Construct validity of grading was present regardless of transplant procedure type or use of mechanical ventilation. Additional severity categories had minimal impact on mortality or biomarker discrimination.