CD147 promotes proliferation and migration of oral cancer cells by inhibiting junctions between E-cadherin and β-catenin.

Anjie MinHaofeng XiongWeiming WangXin HuCan WangTing MaoLiudi YangDanni HuangKun XiaTong Su

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2020)

CD147 plays an important role in tumorigenesis and metastasis by promoting EMT progression in OSCC. It may be considered as a novel potential diagnostic and therapeutic target for OSCC.

Keyphrases

epithelial mesenchymal transition
induced apoptosis
signaling pathway
cell cycle arrest
nk cells
single molecule
endoplasmic reticulum stress
oxidative stress
cell death
risk assessment
climate change