Folic acid antagonist use before and during pregnancy and risk for selected birth defects.
Stephen M KerrSamantha E ParkerAllen A MitchellSarah C TinkerMartha M WerlerPublished in: Birth defects research (2020)
Similar to our previous analyses, we observed associations between AED use and these defects. For DHFRI exposure, we found no evidence for increased risk of these defects. Though statistical power to examine FA effect modification was low, we found no evidence of further protection among those with FA intake ≥400 mcg, with some associations somewhat stronger in this group.
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