Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats.

Bernat Córdoba-JoverAltamira Arce-CerezoJordi RiberaMontse PautaDenise OróGregori CasalsGuillermo Fernández-VaroEudald CasalsVictor PuntesWladimiro JiménezManuel Morales-Ruiz

Published in: Journal of nanobiotechnology (2019)

Our results demonstrate that the nanomaterial cerium oxide, besides their known antioxidant capacities, can enhance hepatocellular proliferation in experimental models of liver regeneration and drug-induced hepatotoxicity.

Keyphrases

oxide nanoparticles
drug induced
liver injury
stem cells
oxidative stress
signaling pathway
adverse drug
anti inflammatory