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Anti-CD20 monoclonal antibody therapy in postpartum women with neurological conditions.

Annika AndersonWilliam RowlesShane PooleAyushi BalanCarolyn BevanRachel BrandstadterAndrea I CipleaJoanna CooperMichelle FabianThomas W HaleDina JacobsMihir KakaraKristen M KryskoErin E LongbrakeJacqueline MarcusPavle RepovicClaire S RileyAndrew R RomeoAlice RutatangwaTimothy WestKerstin HellwigSara C LaHueRiley Bove
Published in: Annals of clinical and translational neurology (2023)
These confirm minimal transfer of mAb into breastmilk. Anti-CD20 mAb therapy stabilizes MS activity before conception to the postpartum period, and postpartum treatments appears to be safe and well-tolerated for both mother and infant.
Keyphrases
  • monoclonal antibody
  • mass spectrometry
  • multiple sclerosis
  • ms ms
  • nk cells
  • blood brain barrier
  • brain injury