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GOLPH3 keeps the Golgi residents at home.

Martin Lowe
Published in: The Journal of cell biology (2021)
In this issue of JCB, Welch et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202106115) show that GOLPH3 mediates the sorting of numerous Golgi proteins into recycling COPI transport vesicles. This explains how many resident proteins are retained at the Golgi and reveals a key role for GOLPH3 in maintaining Golgi homeostasis.
Keyphrases
  • endoplasmic reticulum
  • single cell
  • patient safety
  • cell therapy
  • stem cells
  • mesenchymal stem cells
  • quality improvement
  • bone marrow