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Novel scheme for defining the clinical implications of TP53 mutations in myeloid neoplasia.

Waled BahajTariq KewanCarmelo GurnariArda DurmazBen PonvilawanIshani PanditYasuo KubotaOlisaemeka D OgbueMisam ZawitYazan MadanatTaha BatSuresh K BalasubramanianHussein AwadaRamsha AhmedMinako MoriManja MeggendorferTorsten HaferlachValeria VisconteJaroslaw P Maciejewski
Published in: Journal of hematology & oncology (2023)
Our novel approach more accurately resolves TP53 genomic configuration and uncovers genetic mosaicism for the use in the clinical setting to improve prognostic evaluation.
Keyphrases
  • copy number
  • high grade
  • bone marrow
  • acute myeloid leukemia
  • genome wide
  • dna methylation