Genotoxicity, DNA damage and sperm defects induced by vinblastine.

Maha A FahmyEntesar E HassanAyman A FarghalyZeinab M Hassan

Published in: Molecular biology reports (2022)

VB is genotoxic in somatic and germ cells. Sperm defects induced by VB are of serious concern to future generations and may affect the fertility of cancer survivors.

Keyphrases

dna damage
induced apoptosis
oxidative stress
cell cycle arrest
childhood cancer
young adults
copy number
endoplasmic reticulum stress
dna methylation
embryonic stem cells