Histologic factors associated with nintedanib efficacy in patients with idiopathic pulmonary fibrosis.
Masahiro NemotoYoshiaki ZaizenKensuke KataokaKishio KurodaKazuhiro TabataAndrey BychkovHiromitsu SumikawaTakeshi JohkohMasahiro AoshimaYasuhiro KondohJunya FukuokaPublished in: PloS one (2021)
Edematous changes in the interlobular septum may indicate poor nintedanib efficacy in idiopathic pulmonary fibrosis. Further studies are needed to validate these findings and address the mechanism behind ECIS.