Systemic administration of propranolol reduces bone resorption and inflammation in apical periodontitis of chronically stressed rats.
Rayana Duarte KhouryGiovanna Bignoto MinhotoPatricia Pimentel de BarrosJuliana Campos JunqueiraCarolina Fedel GagliardiRenata Falchete do PradoMarcia Carneiro ValeraPublished in: International endodontic journal (2024)
Oral administration of propranolol had a significant effect on the AP severity in stressed rats, suggesting an anti-inflammatory effect and a protective role on bone resorption of AP in stressed animals. Further research is necessary to fully comprehend the underlying mechanisms.