Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling.

Dongmei Tang Shimei Zheng Zhiwei Zheng Chang Liu Jiner Zhang Renchun Yan Cheng Wu Na Zuo Lijuan Wu Hongfei Xu Shaofeng Liu Yingzi He

Published in: Cell proliferation (2022)

Our results revealed that Dnmt1 is essential for the development of zebrafish auditory organ through regulating cell cycle genes together with Wnt and Fgf signalling pathways.

Keyphrases

cell cycle
cell cycle arrest
cell proliferation
dna methylation
cell death
working memory
pi k akt
stem cells
hearing loss
genome wide identification