A structural equation model to assess the pathways of body adiposity and inflammation status on dysmetabolic biomarkers via red cell distribution width and mean corpuscular volume: a cross-sectional study in overweight and obese subjects.
Mariangela RondanelliSimone PernaTariq A AlalwanRoberta CazzolaClara GasparriVittoria InfantinoFederica PerdoniGiancarlo IannelloDaniele PepeDavide GuidoPublished in: Lipids in health and disease (2020)
The reported outcomes suggest that RDW might play a mediatory role in the relationship between WC and the dysmetabolic outcomes in overweight and obese individuals. CRP seems to modulate the linkage between BMI and MCV. This study provides the backbone structure for future scenarios and lays the foundation for further research on the role of RDW and MCV as suitable biomarkers for the assessment of cardiovascular disease (HDL-cholesterol), inflammatory bowels and insulin resistance.
Keyphrases
- insulin resistance
- cardiovascular disease
- oxidative stress
- type diabetes
- adipose tissue
- body mass index
- single cell
- metabolic syndrome
- climate change
- high fat diet
- weight gain
- cell therapy
- physical activity
- genome wide
- gene expression
- glycemic control
- dna methylation
- cardiovascular risk factors
- high fat diet induced
- hepatitis c virus
- coronary artery disease
- human immunodeficiency virus
- clinical evaluation