Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts.
Yasser SakrBruno FrançoisJordi Solé-ViolanKatarzyna KotfisUlrich JaschinskiAngel EstellaMarc LeoneStephan M JakobXavier WitteboleLuis E FontesMiguel de Melo GurgelThais MidegaJean-Louis VincentV Marco Ranierinull nullPublished in: Critical care (London, England) (2021)
The frequency of and outcome from ARDS remained relatively stable between 2002 and 2012. Plateau pressure > 29 cmH2O and driving pressure > 14 cmH2O on the first day of mechanical ventilation but not tidal volume > 8 ml/kg PBW were independently associated with a higher risk of death. These data highlight the continued burden of ARDS and provide hypothesis-generating data for the design of future studies.