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Choice of Lipid Emulsion Determines Inflammation of the Gut-Liver Axis, Incretin Profile, and Insulin Signaling in a Murine Model of Total Parenteral Nutrition.

Phing-How LouEliana LucchinettiPaulina WawrzyniakYasser MorsyMarcin WawrzyniakMichael ScharlStefanie D KrämerGerhard RoglerMartin HersbergerMichael Zaugg
Published in: Molecular nutrition & food research (2020)
OV-TPN as opposed to IL-TPN mitigates inflammation in the liver and reduces the negative metabolic effects of hyperinsulinemia and hyperglucagonemia by "re-sensitizing" the liver and skeletal muscle to insulin.
Keyphrases
  • skeletal muscle
  • type diabetes
  • oxidative stress
  • adipose tissue