Familial risk of postpartum psychosis.
Adrianna P KępińskaThalia K RobakisKeith HumphreysXiaoqin LiuRené S KahnTrine Munk-OlsenVeerle BerginkBehrang MahjaniPublished in: medRxiv : the preprint server for health sciences (2023)
Increased risk of postpartum psychosis in full siblings is likely due to a combination of genetic factors and shared environment. The elevated risk in cousin pairs, lower than in full siblings, highlights genetic impact because shared environmental effects are assumed to be minimal among cousins. However, caution is needed in interpreting the risk among cousins due to wide confidence intervals. Overall, our study supports the role of genetics and shared environment in the risk of postpartum psychosis.