Endocytosis in anaerobic parasitic protists.
Marlene BenchimolWanderley de SouzaPublished in: Memorias do Instituto Oswaldo Cruz (2024)
The incorporation of different molecules by eukaryotic cells occurs through endocytosis, which is critical to the cell's survival and ability to reproduce. Although this process has been studied in greater detail in mammalian and yeast cells, several groups working with pathogenic protists have made relevant contributions. This review analysed the most relevant data on the endocytic process in anaerobic protists (Entamoeba histolytica, Giardia intestinalis, Trichomonas vaginalis, and Tritrichomonas foetus). Many protozoa can exert endocytic activity across their entire surface and do so with great intensity, as with E. histolytica. The available data on the endocytic pathway and the participation of PI-3 kinase, Rab, and Rho molecular complexes is reviewed from a historical perspective.
Keyphrases
- induced apoptosis
- microbial community
- cell cycle arrest
- wastewater treatment
- electronic health record
- single cell
- endoplasmic reticulum stress
- big data
- physical activity
- oxidative stress
- protein kinase
- stem cells
- signaling pathway
- cell therapy
- machine learning
- high intensity
- bone marrow
- cell proliferation
- data analysis
- saccharomyces cerevisiae
- pi k akt
- artificial intelligence
- single molecule
- solid state