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In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats.

Hai-Bo ZhangFeng-Zhi ChenShu-Hua HeYan-Bing LiangZhi-Qiang WangLi WangZe-Rong ChenWei DingShan-Chao ZhaoAn-Yang Wei
Published in: Stem cell research & therapy (2019)
Myocardin induced ASC differentiation towards smooth muscle-like cells and enhanced the therapeutic potential of ASCs for ameliorating ED in STZ-induced diabetic rats. Notably, in vivo small animal tracking was an effective strategy for monitoring the implanted stem cells, and this strategy might have advantages over traditional EdU assays.
Keyphrases
  • diabetic rats
  • oxidative stress
  • smooth muscle
  • stem cells
  • emergency department
  • gene expression
  • genome wide
  • copy number
  • endothelial cells
  • nlrp inflammasome
  • high glucose