Whole genome sequencing in oncology: using scenario drafting to explore future developments.
Michiel van de VenMartijn J H G SimonsHendrik KoffijbergManuela A JooreMaarten J IJzermanValesca P RetèlWim H van HartenPublished in: BMC cancer (2021)
Based on current expert opinions, the implementation of WGS as a clinical diagnostic in oncology is heavily dependent on the price, clinical utility (both in terms of identifying actionable targets as in adding sufficient value in subsequent treatment), and turnaround time. These aspects and the optimal way of service provision are the main drivers for the implementation of WGS and should be focused on in further research. More knowledge regarding these factors is needed to inform strategic decision making regarding the implementation of WGS, which warrants support from all relevant stakeholders.