Zika virus infects human blood mononuclear cells.
Carolina V MessiasJulia P LemosDaniela P CunhaZilton VasconcelosLidiane M S RaphaelMyrna C BonaldoBruno Cister-AlvesDumith Chequer Bou-HabibVinicius Cotta-de-AlmeidaWilson SavinoDaniella Arêas Mendes-da-CruzPublished in: BMC infectious diseases (2019)
These findings raise the hypothesis that PBMCs can act as a reservoir of the virus, which may facilitate viral dissemination to different organs, including immune-privileged sites.