SERPINE-1 Gene Methylation and Protein as Molecular Predictors of Laparoscopic Sleeve Gastrectomy Outcome.
Sara AssemTamer N AbdelbakiSafaa H Mohy-El DineAmel F KetatDoaa Ali AbdelmonsifPublished in: Obesity surgery (2021)
Baseline SERPINE-1 gene methylation might be a predictor of weight loss after LSG. Meanwhile, postoperative SERPINE-1 protein could be a predictor to weight loss maintenance after LSG. Lastly, postoperative SERPINE-1 gene methylation might serve as an index to postoperative changes in obesity-related comorbidities.
Keyphrases
- weight loss
- genome wide
- bariatric surgery
- patients undergoing
- dna methylation
- copy number
- roux en y gastric bypass
- genome wide identification
- gastric bypass
- metabolic syndrome
- insulin resistance
- protein protein
- gene expression
- small molecule
- single molecule
- binding protein
- skeletal muscle
- physical activity
- obese patients