Challenges in the Complex Management of Neglected Cutaneous Melanomas in the Head and Neck Area: A Single Center Experience.
Péter LázárEdit Tóth MolnárBalázs BendeGábor VassEszter BaltásRóbert PaczonaErika VargaJózsef PiffkóLajos KeményJudit OláhErika Gabriella KisPublished in: Journal of clinical medicine (2023)
Familiar controversies in the management of head and neck melanomas are more remarkable in locally advanced cases, and they represent a treatment challenge both surgically and oncologically. In our retrospective study, patients with surgically treated primary malignant melanoma of the head and neck region larger than 3 cm in diameter were included. Five patients met our inclusion criteria. In all cases, wide excision and immediate reconstruction were performed without sentinel lymph node biopsy. The defect on the scalp was covered by a split skin graft, with local flaps chosen for reconstruction on the face on an individual basis. After a 2-6 year follow-up, a good oncological, functional, and esthetic result was achieved. Our results show that in the case of large, locally advanced melanomas, surgical treatment still plays a crucial role that can provide long-term local control and support the effect of systemic treatment.
Keyphrases
- locally advanced
- rectal cancer
- sentinel lymph node
- neoadjuvant chemotherapy
- squamous cell carcinoma
- newly diagnosed
- ejection fraction
- end stage renal disease
- lymph node
- radiation therapy
- prognostic factors
- phase ii study
- combination therapy
- replacement therapy
- study protocol
- tyrosine kinase
- open label
- robot assisted