ILC2s-Bipartisan politicians in cancer.
Abderezak ZebboudjMasataka AmisakiVinod P BalachandranPublished in: Science immunology (2022)
Group 2 innate lymphoid cells (ILC2s) are lymphocytes that both promote and suppress antitumor immunity. Jou and colleagues now report in colorectal tumorigenesis that the cytokine interleukin-25 activates ILC2s to induce myeloid cells that suppress antitumor immunity.