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Heterozygous mutation of the splicing factor Sf3b4 affects development of the axial skeleton and forebrain in mouse.

Takahiko YamadaMasaki TakechiNorisuke YokoyamaYuichi HiraokaHarumi IshikuboTakako UsamiToshiko FuruteraYuki TagaYoshikazu HirateMasami Kanai-AzumaTetsuya YodaKiyoko Ogawa-GotoSachiko Iseki
Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2020)
Our study suggests that Sf3b4 controls anterior-posterior patterning of the axial skeleton and guarantees cell proliferation for forebrain development in mice.
Keyphrases
  • cell proliferation
  • early onset
  • adipose tissue
  • signaling pathway
  • insulin resistance
  • wild type