Enhanced migration of breast and lung cancer cells deficient for cN-II and CD73 via COX-2/PGE2/AKT axis regulation.

Octavia CadassouMuhammad-Zawwad RazaChristelle MachonLaura GudefinCélia ArmanetKamel ChettabJérôme GuittonMaria Grazia TozziCharles DumontetEmeline Cros-PerrialLars Petter Jordheim

Published in: Cellular oncology (Dordrecht) (2020)

Our results highlight new cell-specific roles of cN-II and CD73 in cancer cell biology and provide insight into their interactions with different intracellular pathways.

Keyphrases

lymph node metastasis
single cell
signaling pathway
nk cells
cell proliferation
cell therapy
bone marrow