DNA methylation dynamic of bone marrow hematopoietic stem cells after allogeneic transplantation.
Stefania TrinoPietro ZoppoliAngelo Michele CarellaIlaria LaurenzanaAlessandro WeiszDomenico MemoliGiovanni CaliceFrancesco La RoccaVittorio SimeonLucia SavinoLuigi Del VecchioPellegrino MustoAntonella CaivanoLuciana De De LucaPublished in: Stem cell research & therapy (2019)
Overall, these data provide insights into the DNA methylation changes of HSPCs after transplantation and a new framework to investigate epigenetics of AHSCT and its outcomes.
Keyphrases
- dna methylation
- bone marrow
- genome wide
- induced apoptosis
- gene expression
- cell cycle arrest
- stem cell transplantation
- mesenchymal stem cells
- cell therapy
- electronic health record
- copy number
- big data
- type diabetes
- endoplasmic reticulum stress
- cell death
- adipose tissue
- skeletal muscle
- pi k akt
- glycemic control
- deep learning