Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma: Real-life Data on Liver Disease, Treatment and Prognosis.

Xavier AdhouteOlivia PietriGuillaume PénarandaThomas WolfPatrick BeaurainOlivier MonnetArthur Laquière Justine BonominiFrédéric NeumannOlivier LevrelJean-Pascal Buono Xavier HannaPaul CastellaniHervé PerrierMarc Bourliere Rodolphe Anty

Published in: Journal of clinical and translational hepatology (2023)

In this French series, cirrhosis was common in iCCA, which showed etiological factors comparable to those of HCC, implying a distinct oncogenic pathway. Both entities had a dismal prognosis at advanced stages. However, systemic therapies sequencing in HCC and molecular profiling in iCCA offer new insights.

Keyphrases

single cell
electronic health record
big data
machine learning
combination therapy
data analysis
drug induced