Cognitive decline associated with anticholinergics, benzodiazepines and Z-drugs: Findings from The Irish Longitudinal Study on Ageing (TILDA).
Frank MoriartyGeorge M SavvaCarlota M GrossiKathleen BennettChristopher FoxIan D MaidmentYoon Kong LokeNicholas SteelRose Anne KennyKathryn RichardsonPublished in: British journal of clinical pharmacology (2020)
Except for new use of anticholinergic medications, no other findings supported a risk of cognitive decline over 2-year periods in this middle-aged and older cohort. Patients and prescribers should weigh this potential risk against potential benefits of commencing anticholinergic medications.