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Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.

Maurizio BaldassarreMarina NaldiGiacomo ZaccheriniMichele BartolettiAgnese AntognoliMaristella LaggettaMartina GagliardiManuel TufoniMarco DomenicaliKatja WaterstradtPaola PateriniAnna BaldanSimona LeoniManuela BartoliniPierluigi VialeFranco TrevisaniMauro BernardiPaolo Caraceni
Published in: Hepatology (Baltimore, Md.) (2021)
This large, observational study provides the evidence in patients with decompensated cirrhosis that eAlb can be quantified and differentiated from tAlb routinely measured in clinical practice. As compared to tAlb, eAlb is more closely associated with disease severity and albumin dysfunction and carries a greater prognostic power. These results prompt future research assessing eAlb as a biomarker for predicting prognosis and treatment response.
Keyphrases
  • heart failure
  • clinical practice
  • ejection fraction
  • liver failure
  • oxidative stress
  • current status
  • solid phase extraction