EDA2R reflects the acute brain response to cranial irradiation in liquid biopsies.

Alejandro Lastra RomeroThea SeitzGeorgios Alkis ZisiadisHolli JefferyAhmed M Osman

Published in: Neuro-oncology (2024)

We propose EDA2R as a promising potential biomarker reflecting irradiation-induced brain injury in liquid biopsies. The levels of EDA2R upon completion of radiotherapy may aid in predicting the severity of IR-induced neurocognitive sequalae at a very early stage after treatment.

Keyphrases

brain injury
early stage
drug induced
high glucose
subarachnoid hemorrhage
diabetic rats
cerebral ischemia
liver failure
radiation therapy
squamous cell carcinoma
bipolar disorder
endothelial cells
sentinel lymph node
locally advanced
lymph node
hepatitis b virus
blood brain barrier
mechanical ventilation