Safety of Vitamin K in mechanical heart valve patients with supratherapeutic INR: A systematic review and meta-analysis.

Bannawich SapapsapChansinee SrisawatPornsinee SuthumpoungOnjira LuengrungkiatNattawut LeelakanokSurasak SaokaewSukrit Kanchanasurakit

Published in: Medicine (2022)

The current evidence does not support the role of low-dose vitamin K as a trigger of thromboembolism in supratherapeutic INR patients with mechanical heart valves. Nevertheless, more well-designed studies with larger sample sizes are required to justify this research question.

Keyphrases

low dose
aortic valve
heart failure
atrial fibrillation
mitral valve
high dose
aortic valve replacement
aortic stenosis
transcatheter aortic valve replacement
case control
coronary artery disease