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Radiographic and histopathological study of gastrointestinal dysmotility in lipopolysaccharide-induced sepsis in the rat.

Marta CastroMarta Sofía ValeroYolanda López-TofiñoLaura López-GómezRocío GirónMaría Isabel Martín-FontellesJose Antonio UrangaRaquel Abalo
Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2023)
Using radiographic, noninvasive methods for the first time, we show that systemic LPS causes dose-, time-, and organ-dependent GI motor effects. Sepsis-induced GI dysmotility is a complex condition whose management needs to take its time-dependent changes into account.
Keyphrases
  • lipopolysaccharide induced
  • inflammatory response
  • acute kidney injury
  • septic shock
  • intensive care unit
  • oxidative stress
  • diabetic rats
  • drug induced