GABAA Receptors in the Mongolian Gerbil: a PET Study Using [18F]Flumazenil to Determine Receptor Binding in Young and Old Animals.

Mariella WeißM MamachR BeutelmannM LukacevicS EilertP BascuñanaA FaselF M BengelJ P BankstahlT L RossG M KlumpG Berding

Published in: Molecular imaging and biology (2021)

Imaging of GABAA receptor binding capacity in gerbils using [18F]FMZ PET revealed SRTM as a simple and robust quantification method of GABAA receptors. Comparison of BPnd in young and old gerbils demonstrated an age-related decrease of GABAA receptor binding.

Keyphrases

binding protein
computed tomography
positron emission tomography
pet ct
dna binding
high resolution
transcription factor
photodynamic therapy
clinical evaluation