The hemodynamic response to co-occurring interictal epileptiform discharges and high-frequency oscillations localizes the seizure-onset zone.
William WilsonDaniel J PittmanPerry DykensVictoria MosherLaura GillJoseph Samuel PeedicailAntis G GeorgeCraig A BeersBradley GoodyearPierre LeVanPaolo Federiconull nullPublished in: Epilepsia (2024)
Intracranial EEG-fMRI can be used to probe the hemodynamic response to HFOs. The hemodynamic response associated with HFOs that co-occur with IEDs better identifies known epileptic tissue than HFOs that occur independently.