Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19.
Yun Kit YeohTao ZuoGrace Chung-Yan LuiFen ZhangQin LiuAmy Yl LiArthur Ck ChungChun Pan CheungEugene Yk TsoKitty Sc FungVeronica ChanLowell LingGavin JoyntDavid Shu-Cheong HuiKai-Ming ChowSusanna So Shan NgTimothy Chun-Man LiRita Wy NgTerry Cf YipGrace Lai-Hung WongFrancis Ka Leung ChanChun Kwok WongPaul Ks ChanWilliam K K WuPublished in: Gut (2021)
Associations between gut microbiota composition, levels of cytokines and inflammatory markers in patients with COVID-19 suggest that the gut microbiome is involved in the magnitude of COVID-19 severity possibly via modulating host immune responses. Furthermore, the gut microbiota dysbiosis after disease resolution could contribute to persistent symptoms, highlighting a need to understand how gut microorganisms are involved in inflammation and COVID-19.