Subcutaneously administered antibiotics: a review.
Marie JumpertzRomain GuilhaumouMatthieu MillionPhilippe ParolaJean-Christophe LagierPhilippe BrouquiNadim CassirPublished in: The Journal of antimicrobial chemotherapy (2022)
The rationale for using SC administration of ceftriaxone, ertapenem and teicoplanin is strong in patients with non-severe infections. It is already commonly practised in some countries, particularly in France. Other antibiotics could be administered subcutaneously, but further studies are needed to validate their use in clinical practice. Further research is needed to safely generalize and optimize this route of administration whenever possible. This would reduce the risk of catheter-related infections and their complications, together with the length of hospital stay.