Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis.

Leonardo Silva de AraujoKevin PesslerKurt-Wolfram SühsNatalia NovoselovaFrank KlawonnMaike KuhnVolkhard KaeverKirsten Müller-VahlCorinna TrebstThomas SkripuletzMartin StangelFrank Pessler

Published in: Journal of translational medicine (2020)

Increased CSF PC ae C44:6 concentrations in bacterial meningitis likely reflect ongoing CNS cell membrane stress or damage and have potential as additional, sensitive biomarker to diagnose bacterial meningitis in patients with less pronounced neuroinflammation.

Keyphrases

cerebrospinal fluid
traumatic brain injury
oxidative stress
blood brain barrier
lipopolysaccharide induced
lps induced
cerebral ischemia
climate change