Interferon Gamma Release Assay and Tuberculin Skin Test Performance in Pregnant Women Living With and Without HIV.
Samantha R KaplanJaclyn N EscuderoJerphason MechaBarbra A RichardsonElizabeth Maleche-ObimboDaniel MatemoJohn KinuthiaGrace C John-StewartSylvia M LaCoursePublished in: Journal of acquired immune deficiency syndromes (1999) (2022)
QFT-Plus assay had higher diagnostic yield than TST for LTBI in WLHIV and HIV-negative women despite lower TB-specific antigen responses in WLHIV. Higher TST positivity was observed in WLHIV. LTBI diagnostic performance in the context of pregnancy and HIV has implications for clinical use and prevention studies, which rely on these diagnostics for TB infection entry criteria or outcomes.
Keyphrases
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- pregnant women
- hepatitis c virus
- hiv aids
- men who have sex with men
- mycobacterium tuberculosis
- pregnancy outcomes
- high throughput
- dendritic cells
- type diabetes
- preterm birth
- adipose tissue
- wound healing
- single cell
- glycemic control