Immunomodulatory and Antiviral Therapy Improved Functional Cure Rate in CHB Patients with High HBsAg Level Experienced NA.

Hongyu JiaGuodong YuJiong YuXiaoli ZhangLisha YangBin WangJiming ZhangLang BaiXinxin ZhangKai WangPing ZhaoDongliang YangYingren ZhaoYanyan YuYimin ZhangJueqing GuChanyuan YeHuan CaiYingfeng LuDairong XiangLiang YuJiangshan LianJianhua HuShanyan ZhangCiliang JinYida Yang

Published in: Journal of clinical and translational hepatology (2023)

In patients with HBeAg-positive chronic hepatitis B and seroconversion after nucleot(s)ide analog treatment, immunomodulatory/antiviral treatment regimens effectively improved HBsAg loss, and the regimen including GM-CSF and HBV vaccination was most effective.

Keyphrases

hepatitis b virus
stem cells
liver failure
mesenchymal stem cells
cell therapy
cerebrospinal fluid
smoking cessation