Neurotrophin-3 Rescues Striatal Synaptic Plasticity in Model of Neurodegeneration by PLC Signaling Activation.

Victor G Gómez-PinedaElizabeth Nieto-MendozaFrancisco Torres-CruzElizabeth Hernández-Echeagaray

Published in: CNS & neurological disorders drug targets (2024)

Our finding highlights the specific involvement of the PLC pathway in the neuroprotective effects of NT-3 in mitigating synaptic dysfunction under neurodegenerative conditions.

Keyphrases

parkinson disease
oxidative stress
mouse model
cerebral ischemia
blood brain barrier