Parkinson-like early autonomic dysfunction induced by vagal application of DOPAL in rats.
Jie SunChao HeQiu-Xin YanHong-Dan WangKe-Xin LiXun SunYan FengRong-Rong ZhaChang-Peng CuiXue XiongShan GaoXue WangRui-Xue YinGuo-Fen QiaoBai-Yan LiPublished in: CNS neuroscience & therapeutics (2021)
These all demonstrate that early autonomic dysfunction mediated by vagal application of DOPAL highly suggests the plausible etiology of PD initiated from peripheral, rather than central site. It will provide a scientific basis for the prevention and early diagnosis of PD.