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ΔNp63 is a pioneer factor that binds inaccessible chromatin and elicits chromatin remodeling.

Xinyang YuPrashant K SinghShamira TabrejeeSatrajit SinhaMichael J Buck
Published in: Epigenetics & chromatin (2021)
Overall, our results demonstrate that ΔNp63 is a pioneer factor that binds nucleosome edges at inaccessible and unmodified chromatin sites and induces histone acetylation and nucleosome repositioning.
Keyphrases
  • dna damage
  • gene expression
  • transcription factor
  • genome wide
  • dna methylation