ΔNp63 is a pioneer factor that binds inaccessible chromatin and elicits chromatin remodeling.
Xinyang YuPrashant K SinghShamira TabrejeeSatrajit SinhaMichael J BuckPublished in: Epigenetics & chromatin (2021)
Overall, our results demonstrate that ΔNp63 is a pioneer factor that binds nucleosome edges at inaccessible and unmodified chromatin sites and induces histone acetylation and nucleosome repositioning.